| dc.creator |
Arıcan, Hülya Mete |
|
| dc.creator |
IŞIK, Ümit |
|
| dc.creator |
Eroğlu, Havvanur |
|
| dc.creator |
BÜYÜKBAYRAM, Halil İbrahim |
|
| dc.date |
2023-01-01T00:00:00Z |
|
| dc.date.accessioned |
2025-02-25T10:19:31Z |
|
| dc.date.available |
2025-02-25T10:19:31Z |
|
| dc.identifier |
3178594c-28d9-4c75-97de-6841ba5d2440 |
|
| dc.identifier |
10.1080/20473869.2023.2298563 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/3178594c-28d9-4c75-97de-6841ba5d2440/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/99258 |
|
| dc.description |
Introduction: The aim of this study is to determine whether there is a difference in serum Zonulin, Occludin, Claudin-5, Junctional Adhesion Molecule-A (JAM-A), Tricellulin levels between individuals diagnosed with Autism Spectrum Disorder (ASD) and healthy controls. Method: A total of 40 children with ASD and 40 controls aged 2-12 years were enrolled in this study. Serum levels of biochemical variables were determined using commercial enzyme-linked immunosorbent assay kits. Childhood Autism Rating Scale, Autism Behavior Checklist and Aberrant Behavior Checklist were applied to determine the severity of autistic symptoms. Results: Serum Zonulin, Occludin, Claudin-5, Tricellulin and JAM-A levels did not differ between the study and control groups. There was no relationship between the severity of ASD symptoms and biochemical parameters. Discussion: Although the findings of the study suggest that the permeability of the Blood Brain Barrier (BBB) is not effective in the etiology of ASD, there is a need for new studies addressing the limitations of our study in a larger and heterogeneous sample in order to generalize the findings. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Serum Zonulin, Claudin-5, junction Adhesion Molecule-A, Occludin and Tricellulin levels in children with autism spectrum disorder |
|
| dc.type |
info:eu-repo/semantics/article |
|