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Multicentric Screening of Local Antibiotic Resistance in Uncomplicated Urinary System Infections: 1850 Patients from 37 Centers Komplike Olmayan Üriner Sistem Enfeksiyonlarında Lokal Antibiyotik Direncinin Çok Merkezli Taranması: 37 Merkezden 1850 Hasta

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dc.creator Aksakalli, Tugay
dc.creator Biçer, Hüseyin
dc.creator Bedir, Selahattin
dc.creator Bayrak, Ömer
dc.creator Balci, Uğur
dc.creator Aydin, Hasan Rıza
dc.creator Çevik, Gökhan
dc.creator Çift, Ali
dc.creator Çiftçi, Halil
dc.creator Coşkun, Burhan
dc.creator Demirdöğen, Şaban Oğuz
dc.creator Demirkol, Mehmet Kutlu
dc.creator Dinçer, Murat
dc.creator Doğan, Ahmet Emin
dc.creator Dursun, Murat
dc.creator Erdemir, Fikret
dc.creator Eryildirim, Bilal
dc.creator Atiş, Gökhan
dc.creator Görür, Sadık
dc.creator Atilla, Mustafa Kemal
dc.creator Hizli, Fatih
dc.creator Yilmaz, Sercan
dc.creator Kadihasanoğlu, Mustafa
dc.creator Usta, Mustafa Faruk
dc.creator Tuncay, Ömer Levent
dc.creator Tuğlu, Devrim
dc.creator Kalkan, Senad
dc.creator Tek, Mesut
dc.creator Karabulut, Ibrahim
dc.creator Sönmez, Mehmet Giray
dc.creator Keskin, Mehmet Zeynel
dc.creator Cinislioğlu, Ahmet Emre
dc.creator Kizilay, Fuat
dc.creator Cinislioğlu, Nazan
dc.creator Köse, Osman
dc.creator Küçük, Eyüp Veli
dc.creator Öztürk, Metin Ishak
dc.creator Oksay, Taylan
dc.creator Odabaş, Öner
dc.creator Şefik, Ertuğrul
dc.creator Akkaş, Fatih
dc.creator Özbey, Isa
dc.creator Kadioğlu, Ateş
dc.creator Erkan, Anıl
dc.date 2024-10-01T00:00:00Z
dc.date.accessioned 2025-02-25T10:19:57Z
dc.date.available 2025-02-25T10:19:57Z
dc.identifier 36dd2dc0-95c3-4c4d-a1ef-b001428404e2
dc.identifier 10.5578/mb.20249658
dc.identifier https://avesis.sdu.edu.tr/publication/details/36dd2dc0-95c3-4c4d-a1ef-b001428404e2/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/99333
dc.description This study was aimed to identify the most frequently observed pathogens in uncomplicated urinary tract infections from outpatient urinary isolates obtained across seven different geographical regions in Türkiye and to determine whether the antibiotic resistance rates of these pathogens differ significantly between these regions. The study included patients aged 18 to 65 years who were diagnosed with uncomplicated urinary tract infections and had positive urine cultures from March 2021 to August 2022, across 37 different centers in Türkiye. The participating centers were selected based on their use of the disk diffusion method, in line with the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines, to ensure standardization of urine culture data. A total of 1850 patients who met the inclusion criteria were included in the study. The analysis of the distribution of antibiotic resistance rates in Escherichia coli isolates revealed statistically significant differences in resistance to ampicillin, fosfomycin and nitrofurantoin across different regions (p< 0.05, p< 0.05, p< 0.05, respectively). The Southeastern Anatolia region was identified as having the highest resistance rates to fosfomycin and trimethoprim-sulfamethoxazole (27.4% and 35.3%, respectively). Additionally, the region with the highest nitrofurantoin resistance was determined as the Eastern Anatolia Region with a rate of 35.7% and the region with the highest ciprofloxacin resistance was determined as the Central Anatolia Region with a rate of 51%.Our study demonstrated that antibiotic resistance in the treatment of uncomplicated urinary tract infections varies by geographical region. We believe this comprehensive, national prospective study will provide valuable insights for clinicians planning empirical treatment for uncomplicated urinary tract infections.
dc.language tur
dc.rights info:eu-repo/semantics/openAccess
dc.title Multicentric Screening of Local Antibiotic Resistance in Uncomplicated Urinary System Infections: 1850 Patients from 37 Centers Komplike Olmayan Üriner Sistem Enfeksiyonlarında Lokal Antibiyotik Direncinin Çok Merkezli Taranması: 37 Merkezden 1850 Hasta
dc.type info:eu-repo/semantics/article


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