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The role of salivary galectin-3 and galectin-9 levels in plaque-induced gingivitis and periodontitis

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dc.creator HATİPOĞLU, MÜKERREM
dc.creator ÖZKAN, AYSUN
dc.creator Bulut, Sule
dc.creator Nalbantoğlu, Ahmet Mert
dc.creator Demir, Zeynep
dc.creator Barut, Zerrin
dc.creator Korkmaz, Hilal
dc.date 2023-09-01T00:00:00Z
dc.date.accessioned 2025-02-25T10:20:49Z
dc.date.available 2025-02-25T10:20:49Z
dc.identifier 42422c7a-7de0-4294-85e0-d53638cfc20a
dc.identifier 10.1016/j.heliyon.2023.e19979
dc.identifier https://avesis.sdu.edu.tr/publication/details/42422c7a-7de0-4294-85e0-d53638cfc20a/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/99493
dc.description Background: This study aimed to compare the salivary galectin-3 and galectin-9 levels in periodontitis, gingivitis, and periodontally healthy patients. Methods: This study included 75 non-smokers who were systemically healthy. The clinical periodontal parameters of each participant were recorded. Individuals with periodontal health, gingivitis, and Stage II or Stage III Grade B periodontitis were allocated to the corresponding study groups (n = 25 each). Saliva samples were obtained from all individuals after they abstained from drinking and eating 1 h before sample collection. The galectin-3 and galectin-9 levels in the saliva were analyzed using enzyme-linked immunosorbent assay. One-way analysis of variance, student's t-test, Spearman correlation, and logistic regression were used for statistical analyses. Results: The galectin-3 and galectin-9 levels were significantly higher in the periodontitis and gingivitis groups than in the healthy group (p < 0.001). The highest galectin-3 and galectin-9 levels were observed in the gingivitis group (p < 0.05). Overall, the galectin-3 levels were significantly higher than the galectin-9 levels in all the groups (p < 0.001). Conclusions: The salivary galectin-3 and galectin-9 levels were high in patients with periodontitis and gingivitis, suggesting that they could be potential biomarkers for periodontal diseases.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title The role of salivary galectin-3 and galectin-9 levels in plaque-induced gingivitis and periodontitis
dc.type info:eu-repo/semantics/article


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