| dc.creator |
Uysal, Sirin |
|
| dc.creator |
Soyer, Zeynep |
|
| dc.creator |
Ayan, Emre Kadir |
|
| dc.date |
2021-01-01T00:00:00Z |
|
| dc.date.accessioned |
2025-02-25T10:23:01Z |
|
| dc.date.available |
2025-02-25T10:23:01Z |
|
| dc.identifier |
6044790a-90b9-4bbf-b206-1b348a62548e |
|
| dc.identifier |
10.2174/1570180818999201224121929 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/6044790a-90b9-4bbf-b206-1b348a62548e/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/99910 |
|
| dc.description |
Background: alpha-Glucosidase is an important hydrolytic enzyme playing a vital role in digestion of carbohydrates. It catalyzes the final step of carbohydrates digestion in biological systems and converts unabsorbed oligosaccharides and disaccharides into monosaccharides, thus resulting in hyperglycemia for diabetic patients. In this respect, it has been considered as a therapeutic target for the treatment of type 2 diabetes since the enzyme inhibition delays carbohydrate digestion and monosaccharide absorption and subsequently reduces postprandial plasma glucose levels. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Synthesis and Enzymological Characterization of Some 2-(Substituted-phenylamino) quinazolin-4(3H)-one Derivatives as Potent alpha-Glucosidase Inhibitors In Vitro |
|
| dc.type |
info:eu-repo/semantics/article |
|