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Determination of Optimum Separation Condition for Some Carbapenem Antibiotics Using RPLC with the Aid of Central Composite Design and Desirability Function

Determination of Optimum Separation Condition for Some Carbapenem Antibiotics Using RPLC with the Aid of Central Composite Design and Desirability Function

ÜSTÜN, Zehra; Daldal, Yasar D.; Gundogan, Busra; ÇUBUK DEMİRALAY, Ebru
URI: http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/66836

Description:

Background: In order to acquire the best chromatographic condition with maximum resolution and minimum analysis time, the central composite design (CCD) added with Derringer's desirability function was utilised in order to separation of doripenem, meropenem and ertapenem.

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