The Celtikci (Burdur) plain is located in the southwest of Turkey and is a semi-closed basin. Groundwater is densely used as drinking, irrigation and domestic water in the plain. Hydrogeochemical processes controlling groundwater chemistry and geochemical assessment of groundwater were investigated in the Celtikci (Burdur/Turkey) plain. In this study, groundwater samples for two seasons were analyzed and major ion chemistry of groundwater was researched to understand the groundwater geochemistry. Two major hydrochemical facies (Ca-HCO3 and Ca-Mg-HCO3) were determined in the area. Various graphical plots and multivariate statistical analysis were used for identifying the occurrence of different geochemical processes. In the study area, weathering is one of the key geochemical processes which controlled the solute concentration in groundwater. Chemical indexes such as sodium adsorption ratio, %Na, residual sodium carbonate, magnesium hazard and permeability index were calculated and results show that groundwater is suitable for irrigation purpose except for permeability index values. Concentrations of Mn, NO3 and total hardness exceed the prescribed limits of WHO and are the major limiting parameters of groundwater use for potable and domestic purposes.