In this study, Mann-Kendall (M-K) trend test was used to observe the temporal variation of precipitation, temperature, and flow data of Manavgat Stream, Köprüçay and Dim Stream sub-basins in the Middle Mediterranean Basin. Also, meteorological drought analysis by using Standardized Precipitation Index (SPI) and Reconnaissance Drought Index (RDI), and hydrological drought analysis by using Streamflow Drought Index (SDI) were performed for this study region. M-K trend test was re-applied to define the temporal variation of standardized meteorological and hydrological drought values obtained in 3-, 6-, 9- and 12-months periods.When the trend analysis results were examined, there was an increasing trend in all stations for the SPI method in the 12- month period, while a decreasing trend was observed in the Manavgat and Alanya stations in the RDI method. In the SDI method, a decreasing trend was detected in all periods.The temporal relationship of these drought indices was tried to be explained for the processes in which significant changes were observed according to the trend test. Therefore, the relationships between flow data and SPI as well as RDI were examined at different lag times. When the relationship between flow values of Dim and Manavgat Stream and both SPI and RDI values was examined, it was obtained a high correlation for four-month delay