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Antibacterial and Anticancer Activities of Violacein Extracted Through Ultrasound-Assisted Extraction Method

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dc.creator Periz, Çağdaş Deniz
dc.creator Ulusoy, Seyhan
dc.creator Boşgelmez Tınaz, Gülgün
dc.creator Şekerler, Turgut
dc.date 2020-10-01T00:00:00Z
dc.date.accessioned 2022-05-10T11:31:39Z
dc.date.available 2022-05-10T11:31:39Z
dc.identifier fc803d35-b890-49c7-ad4d-da1711731fb0
dc.identifier 10.24323/akademik-gida.xxxxxx
dc.identifier https://avesis.sdu.edu.tr/publication/details/fc803d35-b890-49c7-ad4d-da1711731fb0/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/97061
dc.description <p>Violacein is a natural violet pigment produced by various bacterial species, especially by the Gram-negative bacteriaChromobacterium violaceum. Violacein has antibacterial, antifungal, antioxidant and anticancer activities and hasvarious applications in food, cosmetic, textile and pharmaceutical industries. In this study, violacein was extractedfrom the Chromobacterium violaceum culture through ultrasonic-assisted (UA) and microwave-assisted (MA)extraction methods using methanol, ethanol, acetone, and ethyl acetate as solvent. Violacein was quantified usingHigh Performance Liquid Chromatography (HPLC). Then, antibacterial and anticancer activities of these extracts wereinvestigated. In this study, for the first time, the violacein extract was obtained by using UA and MA extractionmethods. The highest violacein concentration could be achieved by UAE method with methanol. It was found out thatviolacein extracts had an antibacterial effect against Staphylococcus aureus, S. aureus (MRSA) and Bacillus cereus.The violacein extract had a strong anticancer effect on cervical cancer (HeLa) cells. Finally, the UA and MA extractionmethods were successfully applied to bacterial cultures in order to extract the violacein.<br></p>
dc.language eng
dc.rights info:eu-repo/semantics/openAccess
dc.title Antibacterial and Anticancer Activities of Violacein Extracted Through Ultrasound-Assisted Extraction Method
dc.type info:eu-repo/semantics/article

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